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Godefridus J Peters Selected Research

Deoxycytidine

1/2020Effect of dexamethasone on the antileukemic effect of cytarabine: role of deoxycytidine kinase.
6/2011Antiproliferative activity, mechanism of action and oral antitumor activity of CP-4126, a fatty acid derivative of gemcitabine, in in vitro and in vivo tumor models.
7/2010Staurosporine increases toxicity of gemcitabine in non-small cell lung cancer cells: role of protein kinase C, deoxycytidine kinase and ribonucleotide reductase.
5/2009Bortezomib induces schedule-dependent modulation of gemcitabine pharmacokinetics and pharmacodynamics in non-small cell lung cancer and blood mononuclear cells.
10/2005In vivo induction of resistance to gemcitabine results in increased expression of ribonucleotide reductase subunit M1 as the major determinant.
8/2004Detection of an alternatively spliced form of deoxycytidine kinase mRNA in the 2'-2'-difluorodeoxycytidine (gemcitabine)-resistant human ovarian cancer cell line AG6000.
4/2002Pretreatment deoxycytidine kinase levels predict in vivo gemcitabine sensitivity.
2/2002Determinants of resistance to 2',2'-difluorodeoxycytidine (gemcitabine).

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Godefridus J Peters Research Topics

Disease

126Neoplasms (Cancer)
04/2022 - 01/2002
42Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
10/2021 - 02/2002
28Pancreatic Neoplasms (Pancreatic Cancer)
02/2022 - 01/2009
18Leukemia
02/2020 - 01/2002
17Lung Neoplasms (Lung Cancer)
10/2021 - 08/2004
15Adenocarcinoma
01/2022 - 01/2009
15Colonic Neoplasms (Colon Cancer)
01/2014 - 08/2003
14Colorectal Neoplasms (Colorectal Cancer)
01/2021 - 06/2007
11Mesothelioma
09/2020 - 08/2003
10Breast Neoplasms (Breast Cancer)
01/2019 - 02/2003
9Neoplasm Metastasis (Metastasis)
01/2021 - 06/2007
9Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
01/2019 - 01/2002
8Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2020 - 04/2004
7Ovarian Neoplasms (Ovarian Cancer)
07/2019 - 08/2004
7Carcinoma (Carcinomatosis)
08/2017 - 03/2003
5Malignant Mesothelioma
03/2022 - 03/2011
5Urinary Bladder Neoplasms (Bladder Cancer)
07/2019 - 02/2002
5Carcinogenesis
05/2019 - 05/2009
4Gout
01/2022 - 12/2011
4Chromosome Aberrations (Chromosome Abnormalities)
12/2016 - 11/2005
3Hypoxia (Hypoxemia)
01/2020 - 03/2011
3Sarcoma (Soft Tissue Sarcoma)
01/2018 - 06/2011
3Glioma (Gliomas)
01/2017 - 01/2017
3Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
10/2016 - 11/2009
3Melanoma (Melanoma, Malignant)
04/2014 - 10/2007
3Xeroderma Pigmentosum (Kaposi's Disease)
08/2013 - 03/2008

Drug/Important Bio-Agent (IBA)

48GemcitabineFDA Link
01/2021 - 02/2002
28Pharmaceutical PreparationsIBA
01/2022 - 01/2002
19Proteins (Proteins, Gene)FDA Link
04/2020 - 04/2002
17DNA (Deoxyribonucleic Acid)IBA
04/2020 - 10/2005
17Cisplatin (Platino)FDA LinkGeneric
01/2020 - 03/2002
15Biomarkers (Surrogate Marker)IBA
03/2022 - 03/2010
15ErbB Receptors (EGF Receptor)IBA
10/2021 - 04/2008
15Fluorouracil (Carac)FDA LinkGeneric
07/2019 - 01/2002
15Thymidylate SynthaseIBA
01/2019 - 01/2002
14Folic Acid (Vitamin M)FDA LinkGeneric
03/2019 - 01/2002
13Tyrosine Kinase InhibitorsIBA
01/2022 - 04/2008
13EnzymesIBA
01/2022 - 02/2003
13Pemetrexed (MTA)FDA Link
01/2020 - 01/2002
12Methotrexate (Mexate)FDA LinkGeneric
07/2019 - 01/2002
12Messenger RNA (mRNA)IBA
01/2018 - 04/2002
11Erlotinib Hydrochloride (CP 358,774)FDA Link
02/2020 - 04/2008
10Folic Acid AntagonistsIBA
01/2020 - 01/2002
10PlatinumIBA
07/2019 - 06/2007
9Phosphotransferases (Kinase)IBA
01/2022 - 10/2005
9Sunitinib (Sutent)FDA Link
01/2022 - 12/2011
9fluorocyclopentenylcytosineIBA
04/2020 - 12/2013
8NucleotidesIBA
04/2022 - 04/2009
8MicroRNAs (MicroRNA)IBA
03/2022 - 01/2012
8NucleosidesIBA
10/2020 - 01/2007
8Cytarabine (Cytosar-U)FDA LinkGeneric
01/2020 - 09/2002
8DeoxycytidineIBA
01/2020 - 02/2002
8Trifluridine (Viroptic)FDA LinkGeneric
06/2014 - 03/2005
7ProdrugsIBA
02/2016 - 05/2007
6CrizotinibIBA
04/2021 - 01/2013
6Sorafenib (BAY 43-9006)FDA Link
01/2021 - 06/2010
6Antineoplastic Agents (Antineoplastics)IBA
01/2020 - 05/2007
6Biological ProductsIBA
01/2020 - 01/2010
6pyrimidineIBA
01/2020 - 01/2007
6CytidineIBA
07/2019 - 12/2013
6multidrug resistance-associated protein 1IBA
01/2019 - 02/2003
6Member 1 Subfamily B ATP Binding Cassette TransporterIBA
01/2019 - 02/2003
6Bortezomib (Velcade)FDA Link
01/2013 - 06/2007
6Gefitinib (Iressa)FDA Link
01/2013 - 03/2010
5Lactate Dehydrogenase 5IBA
02/2022 - 03/2011
5Cytidine DeaminaseIBA
10/2021 - 03/2008
5AntimetabolitesIBA
04/2019 - 06/2007
5trifluridine tipiracil drug combinationIBA
11/2015 - 01/2007
5Thymidine PhosphorylaseIBA
01/2014 - 05/2004
5Ribonucleotide Reductases (Ribonucleotide Reductase)IBA
01/2014 - 10/2005
4Carboplatin (JM8)FDA LinkGeneric
11/2021 - 04/2011
4Drug CombinationsIBA
09/2020 - 01/2006
4Thioguanine (Tioguanine)FDA Link
02/2020 - 11/2009
4Oxaliplatin (Eloxatin)FDA LinkGeneric
07/2019 - 06/2007
4Capecitabine (Xeloda)FDA Link
01/2018 - 12/2011
4RNA (Ribonucleic Acid)IBA
01/2014 - 01/2002
4Proteasome InhibitorsIBA
01/2013 - 09/2008
4Leucovorin (Folinic Acid)FDA Link
12/2011 - 02/2003
4Deoxycytidine KinaseIBA
06/2011 - 04/2002
4Irinotecan (Camptosar)FDA LinkGeneric
07/2009 - 01/2007
3AntibodiesIBA
04/2021 - 01/2018
3ThiadiazolesIBA
09/2020 - 01/2020
3Glucose (Dextrose)FDA LinkGeneric
09/2020 - 09/2003
3indoleIBA
09/2020 - 07/2019
3CytosineIBA
04/2020 - 12/2016
32-mercaptopurineIBA
02/2020 - 11/2009
3Mercaptopurine (6 Mercaptopurine)FDA LinkGeneric
02/2020 - 11/2009
3Tyrosine (L-Tyrosine)FDA Link
02/2020 - 02/2011
3Azathioprine (Imuran)FDA LinkGeneric
02/2020 - 11/2009
3ParaffinIBA
07/2019 - 03/2010
3Uridine KinaseIBA
07/2019 - 01/2014
3MethyltransferasesIBA
04/2019 - 01/2018
3AcridonesIBA
06/2018 - 11/2009
3AminopeptidasesIBA
01/2018 - 04/2014
3L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
12/2016 - 03/2011
3Docetaxel (Taxotere)FDA Link
08/2013 - 01/2008

Therapy/Procedure

43Therapeutics
03/2022 - 03/2002
24Drug Therapy (Chemotherapy)
08/2021 - 03/2002
4Combination Drug Therapy (Combination Chemotherapy)
03/2018 - 12/2011
3Lasers (Laser)
03/2018 - 11/2013